REGULATED INFORMATION

Publication Relating to a Transparency Notification

Mont–Saint–Guibert (Belgium), December 8, 2023, 10.30pm CET / 4.30pm ET "" In accordance with article 14 of the Act of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) announces that it received a transparency notification as detailed below.

On December 6, 2023, Nyxoah received a transparency notification from Deerfield Partners, L.P. indicating that Deerfield Partners, L.P. crossed the 3% threshold on November 30, 2023, after which Deerfield Partners, L.P. holds 856,085 shares, representing 2.99% of the total number of voting rights on November 30, 2023 (28,673,985).

The notification dated December 6, 2023 contains the following information:

• Reason for the notification:
  • Acquisition or disposal of voting securities or voting rights
  • Downward crossing of the lowest threshold
• Notification by: a parent undertaking or a controlling person
• Persons subject to the notification requirement:
  • James E. Flynn
  • Deerfield Partners, L.P. (with address at 345 Park Ave S., 12th FL, New York, NY 10010 United States)
  • Deerfield Mgmt, L.P. (with address at 345 Park Ave S., 12th FL, New York, NY 10010 United States)
  • J.E. Flynn Capital, LLC (with address at 345 Park Ave S., 12th FL, New York, NY 10010 United States)
  • Deerfield Management Company, L.P. (with address at 345 Park Ave S., 12th FL, New York, NY 10010 United States)
  • Flynn Management LLC (with address at 345 Park Ave S., 12th FL, New York, NY 10010 United States)
• Date on which the threshold was crossed: November 30, 2023
• Threshold that is crossed: 3%
• Denominator: 28,673,985

• Notified details:

• Chain of controlled undertakings through which the holding is effectively held: Deerfield Partners, L.P. is controlled by (i) Deerfield Mgmt L.P., which is controlled by J.E. Flynn Capital, LLC and (ii) Deerfield Management Company, L.P., which is controlled by Flynn Management LLC. Both Flynn Management LLC and J.E. Flynn Capital, LLC are controlled by James E. Flynn.
• Additional information: a sale of shares by Deerfield Partners, L.P.

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Contact:
Nyxoah
David DeMartino, Chief Strategy Officer
david.demartino@nyxoah.com
+1 310 310 1313

Attachment

• 2023 12 08 PR Transparency notification 2023 12 (Deerfield) (ENG)

GLOBENEWSWIRE (Distribution ID 1000903425)

REGULATED INFORMATION

Publication Relating to a Transparency Notification

Mont–Saint–Guibert (Belgium), July 27, 2023, 10.30pm CET / 4.30pm ET "" In accordance with article 14 of the Act of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) announces that it received a rectification of an earlier transparency notification.

On July 25, 2023, Nyxoah received the rectification of the April 16, 2023 transparency notification that it had received from ResMed Inc. in relation to the upward crossing of the 5% threshold by ResMed Inc. on March 30, 2023. The correction relates to the number of shares and the percentage of voting rights held by ResMed Inc. on March 30, 2023: ResMed Inc. held 1,619,756 shares, representing 5.73% of the total number of voting rights (and not 1,499,756 shares or 5.30% of the voting rights as stated in the April 2023 notification).

The notification dated July 17, 2023 contains the following information:

• Reason for the notification: acquisition or disposal of voting securities or voting rights
• Notification by: a person that notifies alone
• Persons subject to the notification requirement: ResMed Inc., 9001 Spectrum Center Boulevard, San Diego, CA 92123, USA
• Date on which the threshold was crossed: March 30, 2023
• Threshold that is crossed: 5%
• Denominator: 28,286,985
• Notified details:

• Chain of controlled undertakings through which the holding is effectively held: No indirect holding of voting securities. ResMed Inc. is not a controlled entity.

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Contact:
Nyxoah
David DeMartino, Chief Strategy Officer
david.demartino@nyxoah.com
+1 310 310 1313

Attachment

• 2023 07 27 PR Transparency notification 2023 07 (Resmed) (ENG)

GLOBENEWSWIRE (Distribution ID 1000831958)

PRESS RELEASE
REGULATED INFORMATION

Publication relating to a transparency notification

Mont–Saint–Guibert (Belgium), July 19, 2021, 10.30pm CET / 4.30pm ET "" In accordance with article 14 of the Act of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) announces that it received a transparency notification as detailed below.

On July 16, 2021, Nyxoah received a transparency notification from BNP Paribas Asset Management SA following the passive downward crossing of the lowest threshold on July 7, 2021. As of such date, BNP Paribas Asset Management SA (through its affiliate BNP Paribas Asset Management France SAS) held 696,562 shares, representing 2.79% of the total number of voting rights on July 7, 2021 (25,002,609).

The notification dated July 16, 2021 contains the following information:

• Reason for the notification: passive crossing of a threshold; downward crossing of the lowest threshold
• Notification by: a parent undertaking or a controlling person
• Persons subject to the notification requirement: BNP Paribas Asset Management SA (with address at SA 47000–75318 Parias cedex 09–France)
• Date on which the threshold was crossed: July 7, 2021
• Threshold that is crossed: 3%
• Denominator: 25,002,609
• Notified details:

• Chain of controlled undertakings through which the holding is effectively held: BNP Paribas Asset Management France SAS and BNP Paribas Asset Management UK Ltd are controlled by BNP Paribas Asset Management SA, which in turn is controlled by BNP Paribas SA which benefits from the exemption to aggregate its participations with the participations of its subsidiaries that are investment companies, in accordance with article 21 paragraph 2 of the Royal Decree of 14 February 2008 on the disclosure of large shareholdings.
• Additional information: BNP Paribas Asset Management France SAS is an investment company that exercises voting rights in a discretionary way.

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Contact:

Nyxoah
Fabian Suarez, Chief Financial Officer
fabian.suarez@nyxoah.com
+32 10 22 24 55

Attachment

• 2021 07 20 PR Transparency notification 2021 07 16 (BNP) (ENG)

GLOBENEWSWIRE (Distribution ID 1000517029)

PRESS RELEASE

REGULATED INFOMATION

Publication relating to a transparency notification

Mont–Saint–Guibert (Belgium), July 14, 2021, 10:30pm CET / 4:30pm ET "" In accordance with article 14 of the Act of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) announces that it received a transparency notification as detailed below.

On July 12, 2021, Nyxoah received a transparency notification from Deerfield Partners, L.P. following the acquisition of voting securities or voting rights on July 7, 2021 after which Deerfield Partners, L.P. holds 899,300 shares, representing 3.60% of the total number of voting rights on July 7, 2021 (25,002,609).

The notification dated July 12, 2021 contains the following information:

• Reason for the notification: acquisition of voting securities or voting rights
• Notification by: a parent undertaking or a controlling person
• Persons subject to the notification requirement:
  • James E. Flynn
  • Deerfield Partners, L.P. (with address at 345 Park Ave S, 12th FL, New York, NY 10010 United States)
  • Deerfield Mgmt, L.P. (with address at 345 Park Ave S, 12th FL, New York, NY 10010 United States)
  • J.E. Flynn Capital, LLC (with address at 345 Park Ave S, 12th FL, New York, NY 10010 United States)
  • Deerfield Management Company, L.P. (with address at 345 Park Ave S, 12th FL, New York, NY 10010 United States)
  • Flynn Management LLC (with address at 345 Park Ave S, 12th FL, New York, NY 10010 United States)
• Date on which the threshold was crossed: July 7, 2021
• Threshold that is crossed: 3%
• Denominator: 25,002,609
• Notified details:

• Chain of controlled undertakings through which the holding is effectively held: Deerfield Partners, L.P. is controlled by (i) Deerfield Mgmt L.P., which is controlled by J.E. Flynn Capital, LLC and (ii) Deerfield Management Company, L.P., which is controlled by Flynn Management LLC. Both Flynn Management LLC and J.E. Flynn Capital, LLC are controlled by James E. Flynn.

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Contact:

Nyxoah
Fabian Suarez, Chief Financial Officer fabian.suarez@nyxoah.com
+32 10 22 24 55

Attachment

• 2021 07 14 PR Transparency notification (Deerfield) (ENG)

GLOBENEWSWIRE (Distribution ID 1000516264)